I31V (p.Ile31Val) variant of PIK3CA (P42336)
I31V (p.Ile31Val) in PIK3CA (P42336) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data, published literature, and structural context.
I31V (p.Ile31Val) variant details
- p.Ile31Val
- gnomAD 3-179198916-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.308
- REVEL 0.14
- MetaLR 0.16
- MetaSVM -0.92
- CADD 19.60
- PolyPhen-2 0.00
- SIFT 0.19
- Most common in the Non-Finnish European population (allele frequency 5e-05)
- Structural context available
- Literature evidence available