C36F (p.Cys36Phe) variant of PIK3CA (P42336)
C36F (p.Cys36Phe) in PIK3CA (P42336) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.68 / 1. The record also includes population frequency data, published literature, and structural context.
C36F (p.Cys36Phe) variant details
- p.Cys36Phe
- gnomAD 3-179198932-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.68
- REVEL 0.69
- MetaLR 0.43
- MetaSVM -0.32
- CADD 27.30
- PolyPhen-2 0.94
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 2.3e-05)
- Structural context available
- Literature evidence available