C64Y (p.Cys64Tyr) variant of PIEZO2 (Q9H5I5)
C64Y (p.Cys64Tyr) in PIEZO2 (Q9H5I5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes structural context.
C64Y (p.Cys64Tyr) variant details
- p.Cys64Tyr
- TOPMed rs1719156620
- Missense
- Variant Prioritization Score for Impact Estimate 0.392
- REVEL 0.38
- ESM-1b 0.00
- AlphaMissense 0.81
- MetaLR 0.35
- MetaSVM -0.48
- CADD 24.10
- Structural context available