V84M (p.Val84Met) variant of PIEZO1 (Piezo-type mechanosensitive ion channel component 1)
V84M (p.Val84Met) in PIEZO1 (Piezo-type mechanosensitive ion channel component 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data and structural context.
V84M (p.Val84Met) variant details
- p.Val84Met
- Ensembl rs1905734909
- Missense
- Variant Prioritization Score for Impact Estimate 0.116
- REVEL 0.04
- ESM-1b 0.00
- AlphaMissense 0.14
- MetaLR 0.16
- MetaSVM -1.00
- CADD 8.23
- Most common in the 1KG:CEU population (allele frequency 0.0042)
- Structural context available