L59H (p.Leu59His) variant of PIEZO1 (Piezo-type mechanosensitive ion channel component 1)
L59H (p.Leu59His) in PIEZO1 (Piezo-type mechanosensitive ion channel component 1) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.79 / 1. The record also includes structural context.
L59H (p.Leu59His) variant details
- p.Leu59His
- NCI-TCGA TCGA novel
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.789
- ESM-1b 1.00
- AlphaMissense 0.54
- UniProt: Variant assessed as somatic; moderate impact.
- Structural context available