L35V (p.Leu35Val) variant of PIEZO1 (Piezo-type mechanosensitive ion channel component 1)

Name: PIEZO1 L35V (p.Leu35Val) variant | CATVariant
Creator: Center for Precision Medicine and Data Sciences
Published: 2026-05-15
License: https://catvariant.com/terms-of-use

L35V (p.Leu35Val) in PIEZO1 (Piezo-type mechanosensitive ion channel component 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.64 / 1. The record also includes structural context.

L35V (p.Leu35Val) variant details

p.Leu35Val
TOPMed rs1489239938
gnomAD rs1489239938
Missense
Variant Prioritization Score for Impact Estimate 0.643
ESM-1b 1.00
AlphaMissense 0.21
Structural context available