L25F (p.Leu25Phe) variant of PIEZO1 (Piezo-type mechanosensitive ion channel component 1)
L25F (p.Leu25Phe) in PIEZO1 (Piezo-type mechanosensitive ion channel component 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.13 / 1. The record also includes population frequency data and structural context.
L25F (p.Leu25Phe) variant details
- p.Leu25Phe
- Ensembl rs1906269803
- Missense
- Variant Prioritization Score for Impact Estimate 0.127
- REVEL 0.10
- ESM-1b 0.09
- AlphaMissense 0.08
- MetaLR 0.08
- MetaSVM -0.95
- CADD 0.01
- Population evidence available
- Structural context available