I105T (p.Ile105Thr) variant of PIEZO1 (Piezo-type mechanosensitive ion channel component 1)
I105T (p.Ile105Thr) in PIEZO1 (Piezo-type mechanosensitive ion channel component 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes structural context.
I105T (p.Ile105Thr) variant details
- p.Ile105Thr
- TOPMed rs1905714076
- Missense
- Variant Prioritization Score for Impact Estimate 0.345
- REVEL 0.38
- ESM-1b 0.00
- AlphaMissense 0.19
- MetaLR 0.32
- MetaSVM -0.45
- SIFT 0.02
- Structural context available