p.Pro205delinsLeuSerSer variant of PICALM (Q13492)

Name: PICALM p.Pro205delinsLeuSerSer variant | CATVariant
Creator: Center for Precision Medicine and Data Sciences
Published: 2026-08-21
License: https://catvariant.com/terms-of-use

p.Pro205delinsLeuSerSer in PICALM (Q13492) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.72 / 1. The record also includes population frequency data, published literature, and structural context.

p.Pro205delinsLeuSerSer variant details

gnomAD 11-85960719-G-GAG
Protein Altering
Variant Prioritization Score for Impact Estimate 0.722
CADD 20.90
Most common in the Non-Finnish European population (allele frequency 1.1e-06)
Structural context available
Literature evidence available