V22I (p.Val22Ile) variant of PICALM (Q13492)
V22I (p.Val22Ile) in PICALM (Q13492) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data and structural context.
V22I (p.Val22Ile) variant details
- p.Val22Ile
- TOPMed rs1442635537
- gnomAD rs1442635537
- Missense
- Variant Prioritization Score for Impact Estimate 0.33
- REVEL 0.14
- CADD 19.30
- PolyPhen-2 0.00
- SIFT 0.72
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available