T161P (p.Thr161Pro) variant of PICALM (Q13492)
T161P (p.Thr161Pro) in PICALM (Q13492) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data and structural context.
T161P (p.Thr161Pro) variant details
- p.Thr161Pro
- gnomAD rs1374565778
- Missense
- Variant Prioritization Score for Impact Estimate 0.437
- REVEL 0.29
- CADD 24.40
- PolyPhen-2 0.96
- SIFT 0.32
- Most common in the African/African-American population (allele frequency 3.1e-05)
- Structural context available