P169R (p.Pro169Arg) variant of PICALM (Q13492)
P169R (p.Pro169Arg) in PICALM (Q13492) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.65 / 1. The record also includes population frequency data and structural context.
P169R (p.Pro169Arg) variant details
- p.Pro169Arg
- Ensembl rs2095455902
- Missense
- Variant Prioritization Score for Impact Estimate 0.647
- REVEL 0.54
- CADD 28.20
- PolyPhen-2 0.94
- SIFT 0.00
- Most common in the Latino/Admixed American population (allele frequency 2.3e-05)
- Structural context available