N186S (p.Asn186Ser) variant of PICALM (Q13492)
N186S (p.Asn186Ser) in PICALM (Q13492) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data and structural context.
N186S (p.Asn186Ser) variant details
- p.Asn186Ser
- 1000Genomes rs144544770
- ESP rs144544770
- ExAC rs144544770
- TOPMed rs144544770
- Missense
- Variant Prioritization Score for Impact Estimate 0.392
- REVEL 0.24
- CADD 23.60
- PolyPhen-2 0.09
- SIFT 0.03
- Most common in the 1KG:GWD population (allele frequency 0.0043)
- Structural context available