M159V (p.Met159Val) variant of PICALM (Q13492)
M159V (p.Met159Val) in PICALM (Q13492) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes population frequency data and structural context.
M159V (p.Met159Val) variant details
- p.Met159Val
- 1000Genomes rs373046489
- ESP rs373046489
- ExAC rs373046489
- TOPMed rs373046489
- Missense
- Variant Prioritization Score for Impact Estimate 0.473
- REVEL 0.39
- CADD 23.30
- PolyPhen-2 0.03
- SIFT 0.01
- Most common in the 1KG:CDX population (allele frequency 0.0057)
- Structural context available