M159T (p.Met159Thr) variant of PICALM (Q13492)
M159T (p.Met159Thr) in PICALM (Q13492) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.66 / 1. The record also includes population frequency data and structural context.
M159T (p.Met159Thr) variant details
- p.Met159Thr
- gnomAD rs746285694
- Missense
- Variant Prioritization Score for Impact Estimate 0.655
- REVEL 0.70
- CADD 23.80
- PolyPhen-2 0.25
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 3.6e-06)
- Structural context available