G191R (p.Gly191Arg) variant of PICALM (Q13492)
G191R (p.Gly191Arg) in PICALM (Q13492) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.66 / 1. The record also includes population frequency data and structural context.
G191R (p.Gly191Arg) variant details
- p.Gly191Arg
- gnomAD rs202022146
- Missense
- Variant Prioritization Score for Impact Estimate 0.663
- REVEL 0.57
- CADD 26.80
- PolyPhen-2 0.96
- SIFT 0.00
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available