F76L (p.Phe76Leu) variant of PICALM (Q13492)
F76L (p.Phe76Leu) in PICALM (Q13492) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data and structural context.
F76L (p.Phe76Leu) variant details
- p.Phe76Leu
- ExAC rs755598180
- gnomAD rs755598180
- Missense
- Variant Prioritization Score for Impact Estimate 0.409
- REVEL 0.24
- CADD 23.90
- PolyPhen-2 0.22
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available