F109S (p.Phe109Ser) variant of PICALM (Q13492)
F109S (p.Phe109Ser) in PICALM (Q13492) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.69 / 1. The record also includes population frequency data and structural context.
F109S (p.Phe109Ser) variant details
- p.Phe109Ser
- ExAC rs780443419
- gnomAD rs780443419
- Missense
- Variant Prioritization Score for Impact Estimate 0.689
- REVEL 0.70
- CADD 29.50
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Finnish in Finland (FIN) population (allele frequency 9.4e-05)
- Structural context available