R24G (p.Arg24Gly) variant of PHF6 (PHD finger protein 6)
R24G (p.Arg24Gly) in PHF6 (PHD finger protein 6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data and structural context.
R24G (p.Arg24Gly) variant details
- p.Arg24Gly
- cosmic curated COSV59706
- Missense
- Variant Prioritization Score for Impact Estimate 0.402
- REVEL 0.44
- CADD 23.20
- PolyPhen-2 0.05
- SIFT 0.02
- Most common in the African/African-American population (allele frequency 3.8e-05)
- Structural context available