V83L (p.Val83Leu) variant of PGR (Progesterone receptor)
V83L (p.Val83Leu) in PGR (Progesterone receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data and structural context.
V83L (p.Val83Leu) variant details
- p.Val83Leu
- TOPMed rs1862993021
- Missense
- Variant Prioritization Score for Impact Estimate 0.281
- REVEL 0.07
- CADD 23.30
- PolyPhen-2 0.66
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available