V14L (p.Val14Leu) variant of PGR (Progesterone receptor)
V14L (p.Val14Leu) in PGR (Progesterone receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data and structural context.
V14L (p.Val14Leu) variant details
- p.Val14Leu
- ExAC rs760920621
- TOPMed rs760920621
- gnomAD rs760920621
- Missense
- Variant Prioritization Score for Impact Estimate 0.251
- REVEL 0.09
- CADD 22.40
- PolyPhen-2 0.30
- SIFT 0.05
- Most common in the African/African-American population (allele frequency 0.00015)
- Structural context available