T44I (p.Thr44Ile) variant of PGR (Progesterone receptor)
T44I (p.Thr44Ile) in PGR (Progesterone receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.13 / 1. The record also includes population frequency data and structural context.
T44I (p.Thr44Ile) variant details
- p.Thr44Ile
- ESP rs141862537
- ExAC rs141862537
- TOPMed rs141862537
- gnomAD rs141862537
- Missense
- Variant Prioritization Score for Impact Estimate 0.129
- REVEL 0.05
- CADD 14.80
- PolyPhen-2 0.01
- SIFT 0.05
- Most common in the African/African-American population (allele frequency 7.2e-05)
- Structural context available