T117S (p.Thr117Ser) variant of PGR (Progesterone receptor)
T117S (p.Thr117Ser) in PGR (Progesterone receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data and structural context.
T117S (p.Thr117Ser) variant details
- p.Thr117Ser
- ExAC rs748602793
- TOPMed rs748602793
- gnomAD rs748602793
- Missense
- Variant Prioritization Score for Impact Estimate 0.328
- REVEL 0.06
- CADD 22.60
- PolyPhen-2 0.06
- SIFT 0.03
- Most common in the Middle Eastern population (allele frequency 0.0063)
- Structural context available