S81L (p.Ser81Leu) variant of PGR (Progesterone receptor)
S81L (p.Ser81Leu) in PGR (Progesterone receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
S81L (p.Ser81Leu) variant details
- p.Ser81Leu
- cosmic curated COSV54796
- ExAC rs778465984
- gnomAD rs778465984
- Missense
- Variant Prioritization Score for Impact Estimate 0.207
- REVEL 0.03
- CADD 21.50
- PolyPhen-2 0.01
- SIFT 0.03
- Most common in the Non-Finnish European population (allele frequency 1.2e-05)
- Structural context available