S25P (p.Ser25Pro) variant of PGR (Progesterone receptor)
S25P (p.Ser25Pro) in PGR (Progesterone receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data and structural context.
S25P (p.Ser25Pro) variant details
- p.Ser25Pro
- ExAC rs772873062
- gnomAD rs772873062
- Missense
- Variant Prioritization Score for Impact Estimate 0.191
- REVEL 0.10
- CADD 15.20
- PolyPhen-2 0.01
- SIFT 0.05
- Most common in the South Asian population (allele frequency 2.4e-05)
- Structural context available