S20P (p.Ser20Pro) variant of PGR (Progesterone receptor)
S20P (p.Ser20Pro) in PGR (Progesterone receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data and structural context.
S20P (p.Ser20Pro) variant details
- p.Ser20Pro
- TOPMed rs199841157
- gnomAD rs199841157
- Missense
- Variant Prioritization Score for Impact Estimate 0.258
- REVEL 0.13
- CADD 23.50
- PolyPhen-2 0.08
- SIFT 0.00
- Most common in the Latino/Admixed American population (allele frequency 2.6e-05)
- Structural context available