S108G (p.Ser108Gly) variant of PGR (Progesterone receptor)
S108G (p.Ser108Gly) in PGR (Progesterone receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.07 / 1. The record also includes population frequency data and structural context.
S108G (p.Ser108Gly) variant details
- p.Ser108Gly
- cosmic curated COSV10584
- ExAC rs771726033
- gnomAD rs771726033
- Missense
- Variant Prioritization Score for Impact Estimate 0.072
- REVEL 0.02
- CADD 11.50
- PolyPhen-2 0.01
- SIFT 0.17
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available