R94M (p.Arg94Met) variant of PGR (Progesterone receptor)
R94M (p.Arg94Met) in PGR (Progesterone receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
R94M (p.Arg94Met) variant details
- p.Arg94Met
- cosmic curated COSV10584
- ExAC rs780296630
- TOPMed rs780296630
- gnomAD rs780296630
- Missense
- Variant Prioritization Score for Impact Estimate 0.168
- REVEL 0.03
- CADD 14.60
- PolyPhen-2 0.27
- SIFT 0.04
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available