R62W (p.Arg62Trp) variant of PGR (Progesterone receptor)
R62W (p.Arg62Trp) in PGR (Progesterone receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data and structural context.
R62W (p.Arg62Trp) variant details
- p.Arg62Trp
- cosmic curated COSV54808
- ExAC rs762965993
- gnomAD rs762965993
- Missense
- Variant Prioritization Score for Impact Estimate 0.345
- REVEL 0.11
- CADD 23.40
- PolyPhen-2 0.82
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 6.3e-06)
- Structural context available