Q78E (p.Gln78Glu) variant of PGR (Progesterone receptor)
Q78E (p.Gln78Glu) in PGR (Progesterone receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
Q78E (p.Gln78Glu) variant details
- p.Gln78Glu
- ExAC rs771435218
- TOPMed rs771435218
- gnomAD rs771435218
- Missense
- Variant Prioritization Score for Impact Estimate 0.165
- REVEL 0.03
- CADD 12.40
- PolyPhen-2 0.00
- SIFT 0.19
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available