P35L (p.Pro35Leu) variant of PGR (Progesterone receptor)
P35L (p.Pro35Leu) in PGR (Progesterone receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.13 / 1. The record also includes population frequency data and structural context.
P35L (p.Pro35Leu) variant details
- p.Pro35Leu
- cosmic curated COSV99679
- gnomAD rs1393764426
- Missense
- Variant Prioritization Score for Impact Estimate 0.133
- REVEL 0.06
- CADD 15.30
- PolyPhen-2 0.04
- SIFT 0.02
- Most common in the South Asian population (allele frequency 0.00021)
- Structural context available