P18L (p.Pro18Leu) variant of PGR (Progesterone receptor)
P18L (p.Pro18Leu) in PGR (Progesterone receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data and structural context.
P18L (p.Pro18Leu) variant details
- p.Pro18Leu
- cosmic curated COSV10584
- ExAC rs759568940
- TOPMed rs759568940
- gnomAD rs759568940
- Missense
- Variant Prioritization Score for Impact Estimate 0.156
- REVEL 0.02
- CADD 20.60
- PolyPhen-2 0.03
- SIFT 0.00
- Most common in the Finnish in Finland (FIN) population (allele frequency 9.4e-05)
- Structural context available