P12A (p.Pro12Ala) variant of PGR (Progesterone receptor)
P12A (p.Pro12Ala) in PGR (Progesterone receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
P12A (p.Pro12Ala) variant details
- p.Pro12Ala
- gnomAD rs1300411195
- Missense
- Variant Prioritization Score for Impact Estimate 0.269
- REVEL 0.10
- CADD 22.50
- PolyPhen-2 0.30
- SIFT 0.04
- Most common in the Latino/Admixed American population (allele frequency 2.7e-05)
- Structural context available