L58V (p.Leu58Val) variant of PGR (Progesterone receptor)
L58V (p.Leu58Val) in PGR (Progesterone receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
L58V (p.Leu58Val) variant details
- p.Leu58Val
- ExAC rs751677036
- TOPMed rs751677036
- gnomAD rs751677036
- Missense
- Variant Prioritization Score for Impact Estimate 0.286
- REVEL 0.20
- CADD 22.70
- PolyPhen-2 0.85
- SIFT 0.00
- Most common in the Latino/Admixed American population (allele frequency 0.00011)
- Structural context available