L4P (p.Leu4Pro) variant of PGR (Progesterone receptor)
L4P (p.Leu4Pro) in PGR (Progesterone receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data and structural context.
L4P (p.Leu4Pro) variant details
- p.Leu4Pro
- TOPMed rs1481763731
- gnomAD rs1481763731
- Missense
- Variant Prioritization Score for Impact Estimate 0.116
- REVEL 0.08
- CADD 14.80
- PolyPhen-2 0.01
- SIFT 0.09
- Most common in the Latino/Admixed American population (allele frequency 0.00066)
- Structural context available