L28P (p.Leu28Pro) variant of PGR (Progesterone receptor)
L28P (p.Leu28Pro) in PGR (Progesterone receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data and structural context.
L28P (p.Leu28Pro) variant details
- p.Leu28Pro
- ExAC rs747756907
- gnomAD rs747756907
- Missense
- Variant Prioritization Score for Impact Estimate 0.205
- REVEL 0.09
- CADD 19.40
- PolyPhen-2 0.70
- SIFT 0.02
- Most common in the Non-Finnish European population (allele frequency 9.1e-07)
- Structural context available