L111M (p.Leu111Met) variant of PGR (Progesterone receptor)
L111M (p.Leu111Met) in PGR (Progesterone receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data and structural context.
L111M (p.Leu111Met) variant details
- p.Leu111Met
- ExAC rs759187454
- Missense
- Variant Prioritization Score for Impact Estimate 0.252
- REVEL 0.18
- CADD 23.50
- PolyPhen-2 0.98
- SIFT 0.00
- Most common in the Middle Eastern population (allele frequency 0.0032)
- Structural context available