G8S (p.Gly8Ser) variant of PGR (Progesterone receptor)
G8S (p.Gly8Ser) in PGR (Progesterone receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data and structural context.
G8S (p.Gly8Ser) variant details
- p.Gly8Ser
- Ensembl rs1863012219
- Missense
- Variant Prioritization Score for Impact Estimate 0.223
- REVEL 0.04
- CADD 19.70
- PolyPhen-2 0.03
- SIFT 0.02
- Most common in the African/African-American population (allele frequency 9.2e-05)
- Structural context available