G8C (p.Gly8Cys) variant of PGR (Progesterone receptor)
G8C (p.Gly8Cys) in PGR (Progesterone receptor) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
G8C (p.Gly8Cys) variant details
- p.Gly8Cys
- NCI-TCGA TCGA novel
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.274
- REVEL 0.09
- CADD 23.00
- PolyPhen-2 0.45
- SIFT 0.00
- UniProt: Variant assessed as somatic; moderate impact.
- Population evidence available
- Structural context available