G66R (p.Gly66Arg) variant of PGR (Progesterone receptor)
G66R (p.Gly66Arg) in PGR (Progesterone receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
G66R (p.Gly66Arg) variant details
- p.Gly66Arg
- TOPMed rs1301553115
- gnomAD rs1301553115
- Missense
- Variant Prioritization Score for Impact Estimate 0.272
- REVEL 0.13
- CADD 23.20
- PolyPhen-2 0.68
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 4.8e-05)
- Structural context available