G57W (p.Gly57Trp) variant of PGR (Progesterone receptor)
G57W (p.Gly57Trp) in PGR (Progesterone receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
G57W (p.Gly57Trp) variant details
- p.Gly57Trp
- cosmic curated COSV99678
- 1000Genomes rs3740754
- ExAC rs3740754
- TOPMed rs3740754
- Missense
- Variant Prioritization Score for Impact Estimate 0.325
- REVEL 0.20
- CADD 23.40
- PolyPhen-2 0.97
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available