G57R (p.Gly57Arg) variant of PGR (Progesterone receptor)
G57R (p.Gly57Arg) in PGR (Progesterone receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data and structural context.
G57R (p.Gly57Arg) variant details
- p.Gly57Arg
- 1000Genomes rs3740754
- ExAC rs3740754
- TOPMed rs3740754
- gnomAD rs3740754
- Missense
- Variant Prioritization Score for Impact Estimate 0.2
- REVEL 0.04
- CADD 16.00
- PolyPhen-2 0.01
- SIFT 0.14
- Most common in the Latino/Admixed American population (allele frequency 4.5e-05)
- Structural context available