G34C (p.Gly34Cys) variant of PGR (Progesterone receptor)
G34C (p.Gly34Cys) in PGR (Progesterone receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data and structural context.
G34C (p.Gly34Cys) variant details
- p.Gly34Cys
- ExAC rs757691518
- gnomAD rs757691518
- Missense
- Variant Prioritization Score for Impact Estimate 0.276
- REVEL 0.21
- CADD 19.50
- PolyPhen-2 0.93
- SIFT 0.09
- Most common in the Finnish in Finland (FIN) population (allele frequency 1.9e-05)
- Structural context available