G24V (p.Gly24Val) variant of PGR (Progesterone receptor)
G24V (p.Gly24Val) in PGR (Progesterone receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data and structural context.
G24V (p.Gly24Val) variant details
- p.Gly24Val
- cosmic curated COSV54805
- gnomAD rs1365969218
- Missense
- Variant Prioritization Score for Impact Estimate 0.194
- REVEL 0.07
- CADD 21.10
- PolyPhen-2 0.50
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available