G17C (p.Gly17Cys) variant of PGR (Progesterone receptor)
G17C (p.Gly17Cys) in PGR (Progesterone receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.11 / 1. The record also includes population frequency data and structural context.
G17C (p.Gly17Cys) variant details
- p.Gly17Cys
- TOPMed rs1863009569
- Missense
- Variant Prioritization Score for Impact Estimate 0.112
- REVEL 0.02
- CADD 16.50
- PolyPhen-2 0.06
- SIFT 0.03
- Most common in the South Asian population (allele frequency 0.00021)
- Structural context available