G16D (p.Gly16Asp) variant of PGR (Progesterone receptor)
G16D (p.Gly16Asp) in PGR (Progesterone receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data and structural context.
G16D (p.Gly16Asp) variant details
- p.Gly16Asp
- TOPMed rs962434146
- gnomAD rs962434146
- Missense
- Variant Prioritization Score for Impact Estimate 0.163
- REVEL 0.03
- CADD 17.90
- PolyPhen-2 0.02
- SIFT 0.09
- Most common in the Middle Eastern population (allele frequency 0.00018)
- Structural context available