G123D (p.Gly123Asp) variant of PGR (Progesterone receptor)
G123D (p.Gly123Asp) in PGR (Progesterone receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data and structural context.
G123D (p.Gly123Asp) variant details
- p.Gly123Asp
- TOPMed rs1477586939
- gnomAD rs1477586939
- Missense
- Variant Prioritization Score for Impact Estimate 0.138
- REVEL 0.06
- CADD 11.60
- PolyPhen-2 0.03
- SIFT 0.09
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available