G109R (p.Gly109Arg) variant of PGR (Progesterone receptor)
G109R (p.Gly109Arg) in PGR (Progesterone receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
G109R (p.Gly109Arg) variant details
- p.Gly109Arg
- cosmic curated COSV54797
- TOPMed rs1862986980
- Missense
- Variant Prioritization Score for Impact Estimate 0.167
- REVEL 0.03
- CADD 16.60
- PolyPhen-2 0.07
- SIFT 0.17
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available