F60L (p.Phe60Leu) variant of PGR (Progesterone receptor)
F60L (p.Phe60Leu) in PGR (Progesterone receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
F60L (p.Phe60Leu) variant details
- p.Phe60Leu
- gnomAD rs1472554109
- Missense
- Variant Prioritization Score for Impact Estimate 0.286
- REVEL 0.25
- CADD 23.80
- PolyPhen-2 0.51
- SIFT 0.02
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available