F60C (p.Phe60Cys) variant of PGR (Progesterone receptor)
F60C (p.Phe60Cys) in PGR (Progesterone receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data and structural context.
F60C (p.Phe60Cys) variant details
- p.Phe60Cys
- gnomAD rs1373734471
- Missense
- Variant Prioritization Score for Impact Estimate 0.225
- REVEL 0.16
- CADD 23.10
- PolyPhen-2 0.08
- SIFT 0.02
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available